Background: The relationship between Traffic Air Pollution and asthma symptoms in adolescents is controversial.
Objectives: This study investigates the impact of traffic air pollution on asthma symptoms among adolescents aged 13-14 years in Yazd City, Iran. 
Methods: As part of the Global Asthma Network in Yazd City, Iran, a cross-sectional study was conducted in 2020 involving 5141 adolescents from 48 schools selected via cluster sampling. The study assessed the association between self-reported truck traffic exposure and respiratory symptoms.
Results: Approximately, 31% of adolescents reported frequent exposure to heavy goods vehicles, with a significant association found between truck traffic and asthma symptoms (P=0.001). However, no significant associations were observed between housing types, floor numbers, and asthma (P=0.15 and P=0.11, respectively). Additionally, a significant relationship existed between truck traffic intensity and severe asthma symptoms (P=0.18).
Conclusion: Traffic-related air pollution had a notable impact on asthma symptoms, particularly among male adolescents in Yazd City, Iran.

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