AU - Shadani, Shiva AU - Ghasemi, Fahimeh AU - Kamali, Mahsa AU - Navaeifar, Mohammad Reza AU - Alikhani, Ahmad AU - Alian, Shahriar AU - Davoudi Badabi, Alireza AU - Rezai, Mohammad Sadegh TI - Rabies Virus Infection: A Case Series and Literature Review PT - JOURNAL ARTICLE TA - JPR JN - JPR VO - 10 VI - 4 IP - 4 4099 - http://jpr.mazums.ac.ir/article-1-481-en.html 4100 - http://jpr.mazums.ac.ir/article-1-481-en.pdf SO - JPR 4 ABĀ  - Background: Rabies is a fatal and often neglected disease leading to encephalomyelitis following a bite by an infected mammal. According to the necessity of rabies disease in Iran, we present four cases of rabies virus infection. Case Presentation: We presented 4 cases of rabies virus infection hospitalized in different hospitals in Iran in 2021-2022. Three patients were male. The youngest patient was 6 years old and the oldest was 81 years old. In all 4 cases, RT-PCR detected the positive virus infection. Three cases received rabies immunoglobulin. All of them received at least one dose of rabies vaccination; but, unfortunately, all patients died. Conclusion: The present case series showed the necessity of early rabies vaccination and also the early organization of stray dogs in the community. Unfortunately, two cases were lost to follow-up. So, the population education and follow-up of suspected rabies patients must be taken seriously by healthcare facilities. CP - IRAN IN - Mazandaran University of Medical Sciences LG - eng PB - JPR PG - 315 PT - Case & Review YR - 2022