en Pediatrics Meta-analysis Review Meta-analysis Review <div style="text-align: justify;"><strong>Context</strong>: Musculoskeletal pain is very common among students and adolescents.<br> <strong>Objectives</strong>: The present systematic review and meta-analysis study aimed to determine the prevalence of musculoskeletal pain among Iranian children and adolescents.<br> <strong>Data Sources, Study Selection, and Data Extraction</strong>: All articles on the prevalence of musculoskeletal disorders in Iranian adolescents were searched in the Google Scholar, four Iranian databases and five international English-language databases using the keywords of &ldquo;pain&rdquo;, &ldquo;musculoskeletal disorders&rdquo;, &ldquo;low back pain&rdquo;, &ldquo;adolescents&rdquo;, &ldquo;students&rdquo;, and a combination of these keywords. The obtained data were analyzed by Comprehensive Meta-Analysis (CMA) software.<br> <strong>Results</strong>: The findings showed that out of 9 studies found in this systematic review and meta-analysis, 6 articles were about low back pain, 6 articles about neck pain, and 3 articles about shoulder pain, respectively. According to the findings, 25.4% (95% CI: 19.0 to 33.0) of the children experienced pain; the prevalence rates of low back pain, knee pain, and the shoulder pain were 26.2% (95% CI: 14.3 to 43.0), 22% (95% CI: 14.5 to 32.0), and 29.3% (95% CI: 20.1 to 40.7) in Iranian adolescents, respectively.<br> <strong>Conclusion</strong>: Considering the high prevalence of pain among Iranian adolescents, it is necessary to carry out appropriate interventions for pain prevention among this age group.</div> Pain, Musculoskeletal disorders, Systematic review, Meta-analysis 191 198 http://jpr.mazums.ac.ir/browse.php?a_code=A-10-697-1&slc_lang=en&sid=1 Masoud Hatefi hatefimasoud@yahoo.com 10031947532846003980 10031947532846003980 No Department of Neurosurgery, Faculty of Medicine, Medical University of Ilam, Ilam, Iran. Alireza Abdi a_abdi61@yahoo.com 10031947532846003981 10031947532846003981 No Department of Nursing, Faculty of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran. Asma Tarjoman Asmatarjoman@yahoo.com 10031947532846003982 10031947532846003982 No Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran. Milad Borji miladborji72@gmail.com 10031947532846003983 10031947532846003983 Yes Department of Nursing, Faculty of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran.