en Psychiatry Nursing Review Article Review Article <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Tahoma;"><span style="line-height:2;"><strong>Background</strong>: Divergent findings reported in the literature on the impact of acupressure on improvement in mothers&rsquo; anxiety during labor and consequently on birth outcomes. However, there is no existing meta-analysis on this issue.<br> <strong>Objectives</strong>: This systematic review assesses the effect of acupressure and auriculotherapy on anxiety during labor, neonatal outcomes, and maternal-fetal attachment.<br> <strong>Methods</strong>: The Cochrane central register of controlled trials, MEDLINE/PubMed, ISI, and Scopus online databases were searched by two researchers up to January 2023. The quality of studies was assessed based on the Jade scale.<br> <strong>Results</strong>: Nine studies were included in the systematic review and meta-analysis. Acupressure significantly decreased anxiety compared to touching (standardized mean difference=-3.29; P<0.001; I2=8%; P=0.295; the fixed effect model) and routine care (standardized mean difference=-1.08; confidence interval=-2.46 to 0.30; P=0.12; I2=96.19%; P<0.001). Maternal-fetal attachment was higher in both groups who received acupressure and auriculotherapy compared to the control group (P<0.001). Meanwhile, auriculotherapy did not impact neonatal outcomes, such as newborns&rsquo; weight and Apgar score.<br> <strong>Conclusions</strong>: Acupressure was an effective tool to improve anxiety during labor and it consequently improved fetal oxygenation.</span></span></span></div> Acupressure, Anxiety level, Labor, Systematic review, Meta-analysis, Neonatal outcomes 99 108 http://jpr.mazums.ac.ir/browse.php?a_code=A-10-283-8&slc_lang=en&sid=1 Maryam Mirzaei moghadameh_mirzai@yahoo.com 100319475328460011271 100319475328460011271 No Department of Obstetrics and Gynecology, Faculty of Medicine, Jiroft University of Medical Sciences, Jiroft, Iran. Vahideh Hafezi Siahlarz movahedinia.s84@gmail.com 100319475328460011272 0009-0002-8435-393X No Department of Obstetrics and Gynaecology, Alzahra Hospital, Guilan University of Medical Sciences, Rasht, Iran. Sara Saadat dr.sarasaadat90@gmail.com 100319475328460011273 100319475328460011273 No Division of Nephrology, Department of Pediatrics, Dr Sheikh Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. Firoozeh Mirzaee f_mirzaee@kmu.ac.ir 100319475328460011274 100319475328460011274 No Reproductive and Family Health Research Center, Kerman University of Medical Sciences, Kerman, Iran. Malihe Afiat Milad afiatm@mums.ac.ir 100319475328460011275 100319475328460011275 No Milad Infertility Center, Mashhad University of Medical Sciences, Mashhad, Iran. Masumeh Ghazanfarpour masumeh.ghazanfarpour@yahoo.com 100319475328460011276 100319475328460011276 Yes Reproductive and Family Health Research Center, Kerman University of Medical Sciences, Kerman, Iran.