eng
Mazandaran University of Medical Sciences
Journal of Pediatrics Review
2322-4398
2322-4401
2014-02
2
1
2
9
article
The prevalence of Eczema in Iranian children: A systematic review and Meta-Analysis
Javad Ghaffari
javadneg@yahoo.com
1
Mohammed Reza Navaeifar
dr.navifar@yahoo.com
2
Reza Alizadeh-Navaei
reza_nava@yahoo.com
3
Mazandaran University of Medical Sciences
Mazandaran University of Medical Sciences
Eczema is a very common disorder that affects children. To find out the national prevalence of eczema in Iranian children, we conducted a systematic review and meta-analysis.
We conducted a literature review by using the Google Scholar, PubMed in Medline area, AltaVista, IranMedex and Magiran in August 2013. The search terms included: Prevalence, Eczema, Children, Pediatric, Allergy, ISAAC and Iran. From 156 related articles based on criteria, all the studies performed on children by the International Study of Asthma and Allergies in Childhood protocol that contained eczema manifestations were selected. The required informations from each study included the authors name, date, city, size of population, prevalence of eczema and number of children in elementary school age groups (6-7 years) and junior high school (13-14 years). The information was recorded in designed tables. The extracted data were analyzed by STATA 11.
In this study, we analyzed 16 studies including 56,424 children in whom 28,113 were in 6-7 years age group and 28,311 in 13-14 years age group. The pooled prevalence of eczema in children aged 6-7 years and 13-14 years was 5.98% and 6.52%, respectively.
This review revealed the prevalence of eczema in Iranian children. This information can be helpful to identify and control eczema symptoms in children suffering from allergic disorders.
http://jpr.mazums.ac.ir/article-1-66-en.pdf
Prevalence
Eczema
Children
Allergy
ISAAC
Iran
eng
Mazandaran University of Medical Sciences
Journal of Pediatrics Review
2322-4398
2322-4401
2014-02
2
1
10
16
article
Prevalence of Celiac Disease in Type 1 Diabetes Mellitus Children: A review of literatures in the Islamic Republic of Iran
Daniel Zamanfar
1
Mohsen Aarabi
aarabi@mazums.ac.ir
2
Iman Sadeghian
3
Mazandaran University of Medical Sciences
Mazendaran University of Medical Sciences
Type 1 Diabetes Mellitus (T1DM) is the most chronic metabolic disorder in children. Celiac disease or gluten-sensitive enteropathy is a genetic and autoimmune disease which results from immune reaction to gluten. Therefore like type 1 diabetes mellitus, celiac disease is triggered by an environmental exposure in genetically susceptible individuals. The aim of this study was to review the articles reporting the prevalence of celiac disease in patients with type 1 diabetes in Iran. The results can be used for comparison with other countries, and also emphasizes the importance of screening for this disease in these patients. In this study, the articles published in PubMed, Google Scholar, Scientific Information Database (SID), Magiran and Iranmedex databases were reviewed. Three published studies (1 cross-sectional and 2 case-control) had been found and described the prevalence of celiac disease in patients aged 2-18 years with type 1 diabetes in Iran. The reported prevalence was between 3.4% and 6.8%. This is similar to reports from other countries however more studies are warranted.
http://jpr.mazums.ac.ir/article-1-62-en.pdf
Diabetes mellitus
Celiac Disease
Prevalence
Iran
children
eng
Mazandaran University of Medical Sciences
Journal of Pediatrics Review
2322-4398
2322-4401
2014-02
2
1
17
28
article
Cutaneous manifestation in children with HIV/AIDS
Seyed Naser Emadi
1
Shrikank Mansukhlal Bhatt
2
James Machoki M’Imunya
3
Andrew Juma Suleh
4
Seyed Reza Raeeskarami
5
Mohammad Sadegh Rezai
drmsrezaeii@yahoo.com
6
Mohammad Reza Navaeifar
7
The most recent studies have explained almost 2.3 million children are affected with HIV up to the end of 2009. Sub-Saharan Africa is the main region to at least 68% of the global total of HIV infection of 22.5 million. Despite providing competent healthcare services to prevent mother-to-child transmission which is the main way of infection to a newborn, an estimated 370,000 children were newly infected in 2009. Skin disorders are common and may even be the first manifestation of HIV in children. The most common skin illnesses are classified in four groups infections, inflammatory, neoplasm, and HAART related. In addition, unusual anatomical sites and disseminated skin lesions, increased frequency and severity, unexplained clinical presentation and rapid onset, and finally treatment failure may be the other specified skin conditions in HIV/AIDS children. CD4 count and viral load are two basic factors playing an almost important role in terms of type and severity of skin illness. The aim of this review was to show the common and crucial cutaneous finding among HIV/AIDS children via published articles with the same subject.
http://jpr.mazums.ac.ir/article-1-68-en.pdf
HIV
AIDS
Children
Skin
eng
Mazandaran University of Medical Sciences
Journal of Pediatrics Review
2322-4398
2322-4401
2014-02
2
1
29
38
article
Update on Infantile Haemangioma
Zohreh Hajheydari
zhajheidari@mazums.ac.ir
1
Soheila Shahmohammadi
sosha1965@gmail.com
2
Rezvan Talaee
3
Journal of Pediatric Review Office
Kashan University of Medical Sciences
Infantile Haemangiomas (IH) are the most common vascular tumors occurring in early childhood, with a prevalence of approximately 5-10% of infants. These vascular tumors are divided into two main groups including infantile haemangioma and vascular malformations. Although, haemangioma of infancy are common, benign and self-limited tumors, a significant percent of these lesions are associated with substantial morbidity in infancy and childhood. All currently used treatments have significant risks. Dramatic improvement of complicated haemangioma of infancy to propranolol was recently reported. Herein, we review infantile haemangioma as a whole with focus on the therapeutic efficacy of systemic and topical propranolol as a beta-blockers for the management of infantile haemangioma.
http://jpr.mazums.ac.ir/article-1-64-en.pdf
Beta-Blockers
Propranolol
Infantile haemangiomas
eng
Mazandaran University of Medical Sciences
Journal of Pediatrics Review
2322-4398
2322-4401
2014-02
2
1
39
46
article
Update on Hyper IgE syndrome (HIES)
Javad Ghaffari
javadneg@yahoo.com
1
Hamid Ahanchian
ahanchianh@mums.ac.ir
2
Fariborz Zandieh
3
Hyper IgE Syndrome (HIES) is a rare primary immunodeficiency disease. Most of HIES cases are sporadic. HIES type AD is caused by mutation in signal transducer and activator of transcription-3 (STAT-3). A number of mosaicism HIES has been reported that is associated with intermediate phenotype. Autosomal recessive HIES (AR-HIES) is due to mutation in Dock-8 or cytokine sis 8 and TYK2 or tyrosine kinase 2. The common manifestations are atopic eczema, staphylococcal dermatitis, cellulitis and folliculitis (cold dermal abscesses that are not warm, painful and without redness), recurrent pneumonia and pulmonary abscesses, osteopenia and recurrent bone fracture. The diagnosis of standard HIES is based on clinical suspicion. There is no specific treatment for HIES. The treatment should be based on the prevention of developing infections. Prophylactic antibiotics such as cotrimoxazole and IVIG are administered. Hematopoietic stem cell transplantation was done for all types of HIES, but there is a little information and experience about the long term results of this therapy.
http://jpr.mazums.ac.ir/article-1-65-en.pdf
Hyper IgE Syndrome
infection
Immunodeficiency
eng
Mazandaran University of Medical Sciences
Journal of Pediatrics Review
2322-4398
2322-4401
2014-02
2
1
47
54
article
Prenatal diagnosis in Islamic countries: A narrative review in 2013
Mehrnoush Kosaryan
mekowsarian@gmail.com
1
Khadijeh Rabiei
mprabie@yahoo.com
2
Thalassemia Research Center, Mazandaran University of Medical Sciences
Traditional and Complementary Medicine Research Center, Mazandaran University of Medical Sciences
Objective: To review the current situation regarding prenatal diagnosis (PND) in Islamic countries.
Methods: A descriptive study (narrative review) has been done based on the available data in formal international and national published documents in 2013. The sources were papers, websites and electronic books. Time limitation of searches has started 20 years ago. The main languages were English and Persian.
Results: Frothy seven nations were officially referred as Islamic since more than 50% of the citizens are Muslims. The holy Qur'an and Islamic traditions (Shari'aht) are the core of the civil laws, however, the legal grounds for prenatal diagnosis differ in Islamic countries. The main ground is the endangerment of a mother's life, however, severe suffering of parents (Osr va Haraj) is also considered in the Islamic Republic of Iran. Some other important issues such as pregnancies as a result of rape should be discussed more in some Islamic countries. Many “hard to treat diseases” such as chromosomal disorders, major hemoglobinopathies, inborn error of metabolism, Duchene muscular dystrophy, spinal muscular dystrophy are being diagnosed early in embryonic period that medical abortion is advisable.
Conclusion: Prenatal diagnosis is an acceptable practice in both religious and secular governments in the so-called Islamic countries.
http://jpr.mazums.ac.ir/article-1-63-en.pdf
Prenatal diagnosis
Islam
Medical abortion
Ethics
Holly Quran
eng
Mazandaran University of Medical Sciences
Journal of Pediatrics Review
2322-4398
2322-4401
2014-02
2
1
55
61
article
Mental health status in patients with Thalassemia major in Iran
Mahdieh Nasiri
nasiri_mahdie@yahoo.com
1
Hamzeh Hosseini
hosseinish20@gmail.com
2
Soheila Shahmohammadi
sosha1965@gmail.com
3
Mazandaran University of Medical Sciences
Thalassemia major is a genetic blood disorder that is detected by the symptoms of chronic and severe anemia, failure to thrive, an enlarged liver and spleen, bone deformities particularlya deformed face and bulging forehead. Due to changes in physical appearance, the disease can influence on other aspects of the patient's life, so the disease could strongly impact on the mental health of these patients and their families. Previous studies show that 80% of patients with thalassemia major have at least one psychiatric disorder. The aim of this paper is to review the mental health status of patients with Beta-thalassemia major in Iran.
http://jpr.mazums.ac.ir/article-1-56-en.pdf
Thalassemia Major
Mental Health
Psychiatric disorder
eng
Mazandaran University of Medical Sciences
Journal of Pediatrics Review
2322-4398
2322-4401
2014-02
2
1
62
74
article
BCG-osis after BCG vaccination in immunocompromised children: Case series and review
Soheila Shahmohammadi
sosha1965@gmail.com
1
Mohammad Jafar Saffar
saffar@softhome.net
2
Mohammad Sadegh Rezai
drmsrezaii@yaoo.com
3
Bacillus Calmette Guerin (BCG) developed by Albert Calmette and Camille Guerin in France between 1908 and 1921 contained a live attenuated strain of Mycobacterium bovis and was administered worldwide to prevent tuberculosis. BCG vaccination is also administered at birth to all the newborns in Iran. Disseminated BCG infection after BCG vaccination is rare. Here in, we report 2 new cases of disseminated BCG infection and review 15 additional cases identified from our previous retrospective study during a 5-year period from 2005-2010. All of these reported patients were vaccinated. Impaired immunity was detected in 10 cases (59%) including severe combined immunodeficiency, chronic granulomatous disease, Mendelian susceptibility to mycobacterial disease, combined variable immunodeficiency, and HIV infection. Response to therapy was poor among those patients with immune deficiencies, but the overall mortality rate was 32.3%. Disseminated BCG infection is a rare but devastating complication of vaccination. Immune-compromised children are at high risk of developing BCG related complications including regional BCG-itis or disseminated disease BCG-osis.
http://jpr.mazums.ac.ir/article-1-67-en.pdf
BCG-osis
Disseminated BCG infection
Immunodeficiency
Mendelian susceptibility to mycobacterial disease
Children
eng
Mazandaran University of Medical Sciences
Journal of Pediatrics Review
2322-4398
2322-4401
2014-02
2
1
75
76
article
The best time for circumcision?
seyed abdollah Mousavi
Dr.a.mosavi@gmail.com
1
http://jpr.mazums.ac.ir/article-1-69-en.pdf