دوره 10، شماره 1 - ( 11-1400 )                   جلد 10 شماره 1 صفحات 72-67 | برگشت به فهرست نسخه ها


XML English Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Saffari F, Arad B. Treatment of Hypertension in a Child With 11Beta-Hydroxylase Deficiency: A Case Report. J. Pediatr. Rev 2022; 10 (1) :67-72
URL: http://jpr.mazums.ac.ir/article-1-421-fa.html
Treatment of Hypertension in a Child With 11Beta-Hydroxylase Deficiency: A Case Report. Journal of Pediatrics Review. 1400; 10 (1) :67-72

URL: http://jpr.mazums.ac.ir/article-1-421-fa.html


چکیده:   (2048 مشاهده)
Background: 11beta-hydroxylase deficiency (11βOHD) is clinically presented with external genitalia virilization in girls and precocious puberty in boys. Low renin hypertension occurs in both sexes. Early diagnosis and treatment of hypertension can prevent complications.
Objectives: To provide a practical management for controlling hypertension in patients with 11-beta-hydroxylase deficiency.
Methods: We described a 4.5 years old girl of 46.XX, who presented with ambiguous genitalia at birth and hypertension later in follow-up. The patient had received the appropriate dosage of hydrocortisone and the level of 17-hydroxy progesterone was within the acceptable range but the hypokalemia persisted. Both hypertension and hypokalemia were normalized when spironolactone was added.
Results: Blocking mineralocorticoid receptor treat hypertension in 11-beta-hydroxylase deficiency.
Conclusions: Intermittent measurement of blood pressure is necessary for patients with 11βOHD. In these patients, spironolactone is effective in treating mineralocorticoid-mediated hypertension and hypokalemia by blocking mineralocorticoid receptors.
متن کامل [PDF 349 kb]   (929 دریافت)    
نوع مطالعه: Case Report and Review of Literature |
دریافت: 1400/4/20 | پذیرش: 1400/7/18 | انتشار: 1400/10/11

ارسال نظر درباره این مقاله : نام کاربری یا پست الکترونیک شما:
CAPTCHA

بازنشر اطلاعات
Creative Commons License این مقاله تحت شرایط Creative Commons Attribution-NonCommercial 4.0 International License قابل بازنشر است.

کلیه حقوق این وب سایت متعلق به Journal of Pediatrics Review می باشد.

طراحی و برنامه نویسی : یکتاوب افزار شرق

© 2024 CC BY-NC 4.0 | Journal of Pediatrics Review

Designed & Developed by : Yektaweb