TY - JOUR JF - JPR JO - J. Pediatr. Rev VL - 10 IS - 4 PY - 2022 Y1 - 2022/12/01 TI - COVID-19 in Children With Inflammatory Bowel Disease: A Systematic Review TT - N2 - Background: Considering the chronic immunosuppression in inflammatory bowel disease (IBD) patients, it is necessary to evaluate the course of COVID-19 in these patients. Studies have shown various results in adult IBD patients. This study aimed to find out the course of this infection in pediatric IBD patients. Methods: This was a systematic review study according to the PRISMA 2020 guideline. International databases including Scopus, PubMed, and the Web of Science were searched with a combination of “COVID-19” AND “IBD” or synonyms until October 16, 2021. Studies that have reported the outcomes of COVID-19 infection in patients less than 19 years of age were selected. Name of author, country, study duration and type, IBD type and drugs, and COVID-19 outcomes were extracted. Results: From the initially retrieved 2215 articles, finally 16 articles were eligible. Data from 1040 pediatric IBD patients were reported. Twenty-four patients were hospitalized, 5 developed patients multisystem inflammatory syndrome in children, and others had a mild disease course and were outpatient. Steroid use, severe IBD activity, and comorbidities were shown to increase risk of hospitalization and disease severity. Conclusion: COVID-19 is a benign and self-limited disease in pediatric IBD patients. Comorbidities, steroid use, and severe IBD activity affect the outcomes. SP - 277 EP - 286 AU - Nasri, Peiman AU - Sadeghi, Somayeh AU - Hovsepian, Silva AU - Chegini, Rojin AU - Soltani Esmaeili, Shahrzad AU - Kiani, Gelareh AD - Department of Pediatrics, School of Medicine, Imam Hossein Children’s Hospital, Isfahan University of Medical Sciences, Isfahan, Iran. KW - Coronavirus disease 2019 KW - Inflammatory bowel disease KW - SARS-CoV-2 KW - Pediatrics UR - http://jpr.mazums.ac.ir/article-1-476-en.html DO - 10.32598/jpr.10.4.1059.1 ER -