2024-03-28T16:37:59+03:30 http://jpr.mazums.ac.ir/browse.php?mag_id=22&slc_lang=en&sid=1
22-241 2024-03-28 10.1002
Journal of Pediatrics Review J. Pediatr. Rev 2322-4398 2322-4401 10.32598 2020 8 3 The Therapeutic Effect of Zinc Sulfate in Iranian Neonates With Hyperbilirubinemia: A Systematic Review and Meta-Analysis Gholamreza Kalvandi Mehdi Shokri Hamed Tavan hamedtavan@gmail.com Background: Physiologic jaundice in neonates usually occurs during the first week of life. The main cause of this condition is increased serum bilirubin due to heme catabolism. Objectives: This systematic review and meta-analysis study aimed to investigate the therapeutic effect of zinc sulfate in Iranian newborns with hyperbilirubinemia. Methods: This review was performed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol. The databases of ISI, Cochrane Library, Google Scholar, PubMed, and Scopus were independently searched by two researchers using MeSH keywords. We included the studies published in different regions of Iran from 2015-2018. The obtained data were analyzed using the meta-analysis technique and STATA. To determine the heterogeneity across the studies, the Q and I square (I2) indices were used. Results: A total of 40 articles were collected from which 5 studies with adequate quality entered the systematic review process. The collected results were assessed in the intervention (zinc sulfate recipients) and control (without zinc sulfate treatment) groups. After the first day of consumption, total serum bilirubin level decreased 4.46 mg/dL (I2=61.9%, P=0.049) and 4.08 mg/dL (I2=72.9%, P=0.011) in the intervention and comparison groups, respectively. In the second and third days, the mean values of decreases in serum bilirubin reached 7.64 mg/dL and 6.66 mg/dL in the intervention and comparison groups, respectively. From the third day onward, serum bilirubin dropped by 8.46 and 7.08 mg/dL in intervention and control groups, respectively. Meta-regression analysis data based on the sample size and year of the study indicated a significant growing trend in using zinc sulfate by increasing years and sample size. Conclusions: Zinc sulfate is a safe and effective medication in reducing bilirubin level and its usage has increased in recent years. Therefore, this supplement could be used for the treatment of neonatal hyperbilirubinemia. Therapy Infant Treatment Zinc sulfate 2020 7 01 145 152 http://jpr.mazums.ac.ir/article-1-241-en.pdf 10.32598/jpr.8.3.834.1
22-276 2024-03-28 10.1002
Journal of Pediatrics Review J. Pediatr. Rev 2322-4398 2322-4401 10.32598 2020 8 3 Relationship Between Breast Milk Ghrelin and Infants’ Serum Ghrelin and Growth in Breastfeeding Infants: A Systematic Review and Meta-Analysis Maryam Soori Younes Mohammadi Mohammad Taghi Goodarzi mtgoodarzi@yahoo.com Minoo Mahmoodi Background: There is positive correlation between infant serum ghrelin and the growth of infants in breastfed infants. Objectives: The present study aimed to evaluate of the relationship between breast milk ghrelin and serum ghrelin and growth in breast-milk-fed infants by systematic review and meta-analysis approaches. Methods: Electronic resources used in the current search were Scopus, Cochrane Library, Science Direct, PubMed, and EMBASE. The English language full-text articles and abstracts published from 1999 to July 2019 were collected. Only the articles that explored infants under two years of age and receiving breast milk exclusively were reviewed. Papers related to healthy mothers and infants were entered in this study. The results of 6 papers regarding the effect of serum ghrelin on the growth of infants, i.e., evaluated by meta-analysis using Stata software. The data addressing the effect of breast milk ghrelin on growth were reported by a systematic review manner; three articles were found in this area. We used Preferred Reporting Items for systematic reviews and meta-analyses (prisma) checklist for performing this study. Results: In this study, the association of infants’ serum ghrelin with infants’ growth was evaluated by meta-analysis. Newcastle-Ottawa Scale (NOS) value was ≥7scores for the 6 explored meta-analysis articles. The present meta-analysis research suggested a positive and significant correlation between infant serum ghrelin and the growth of infants (r=0.163).  Conclusions: The random-effect model data demonstrated a positive and significant correlation between infant serum ghrelin and the growth of infants. However, in the study of the effect of breast milk ghrelin on infants’ growth, the number of articles was limited and contradictory results were reported. Accordingly, no general conclusion was reached.  Ghrelin Body Mass Index (BMI) Weight for length Meta-analysis Systematic review 2020 7 01 153 162 http://jpr.mazums.ac.ir/article-1-276-en.pdf 10.32598/jpr.8.3.868.1
22-260 2024-03-28 10.1002
Journal of Pediatrics Review J. Pediatr. Rev 2322-4398 2322-4401 10.32598 2020 8 3 Health Literacy Measurement in Childhood: A Systematic Review Kobra Abedian Kasgari kobra_abedian1384@yahoo.com Nooshin Peyman peymann@mums.ac.ir Safa Momeni Badeleh Mo23@yahoo.com Mehdi Gholian Avval gholianam@mums.ac.ir Kosar Momeni Badeleh Kosarmomeni@yahoo.com Mohammad Vahedian Shahroodi vahedianm@mums.ac.ir Seyedeh Belin Tavakoly Sany tavakkolisanib@mums.ac.ir Background: Children constitute the main target population for Health Literacy (HL) research. There is limited academic agreement and measurement regarding the knowledge and skills of children concerning making health decisions.  Objectives: This review aimed to address this gap of data by providing an outline of current studies of HL in childhood. Moreover, we attempted to comprehend available theories and models concerning the needs and characteristics of children.  Methods: Six databases, including Scopus, PubMed, Cumulative Index to Nursing, Educational Resources Information Centre (ERIC), Web of Science, and Allied Health Literatures (CINAHL) were systematically searched using relevant keywords regarding HL and childhood. We included the relevant publications of up to July 2019. Interventional and cross-sectional studies with main focuses on generic HL and relevant content for conceptualizing and defining HL in children were included in this research. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline was used to design this review study.  Results: Overall, 25 studies conceptualized and defined HL; 8 definitions and 9 models have specifically focused on children aged 3-18 years. HL in children is defined as several main dimensions, each emerging as a collection of related ability, knowledge, and skills that allow an individual to derive at health-promoting actions and decisions, and approach health data, effectively.  Conclusions: Identified models and definitions are highly diverse, signifying HL concepts are complex, multidimensional, and constructive. HL has been conceptualized as an action qualification, with the main attention on individual attributes, and understanding its interrelationship with sociocontextual factors. Life phase specialty is mostly conceptualized from disregarding children’s specific needs, developmental viewpoint, susceptibilities, and social structures poorly synthesized within most definitions and models.  Health literacy Childhood Child health 2020 7 01 163 174 http://jpr.mazums.ac.ir/article-1-260-en.pdf 10.32598/jpr.8.3.850.1
22-265 2024-03-28 10.1002
Journal of Pediatrics Review J. Pediatr. Rev 2322-4398 2322-4401 10.32598 2020 8 3 Post-Kidney Transplantation Epstein-Barr Virus Infection in Children: Case Series Study Behnam Sobouti Hasan Otukesh Farnoosh Seirafianpour Shahrbanoo Nakhaie Nahid Rahimzadeh Shirin Sayyahfar Rozita Hoseini rozitahoseini@yahoo.com Background: One of the main problems following organ transplantation is the spread of various microbial infections, especially opportunistic infections, including Epstein-Barr Virus (EBV).  Objectives: We aimed to determine the prevalence rate of EBV infection in children undergoing kidney transplantation by recognizing the virus titers before and after transplantation. Methods: In this case series study, 16 children who underwent kidney transplantation and hospitalization were retrospectively assessed. The EBV serology was assessed by virus Deoxyribonucleic Acid (DNA) quantitative assessment using the Polymerase Chain Reaction (PCR) technique. A brief review was also performed on post-kidney transplantation EBV infection in the explored children. Results: All studied patients were seronegative for EBV before transplantation; while two (12.5%) male children had positive serology after transplantation with the loads of 278 copies/mL and 14655 copies/ML, and none resulted in the rejection of kidney transplantation. The duration after transplantation was significantly longer in those children with positive serology after transplantation (P=0.025). No significant association was detected between the serological positivity for EBV and patients’ gender, causes for kidney insufficiency before transplantation, baseline underlying disorders, initial medications, the type of donor, and the mean age. Conclusions: Among the investigated children undergoing renal transplantation, none were seropositive to EBV before transplantation; while 12.5% have been converted to EBV seropositivity after transplantation. The odds of EBV seropositivity was only linked to the time interval from the transplantation.  Kidney transplantation Epstein-Barr Virus (EBV) infection 2020 7 01 175 180 http://jpr.mazums.ac.ir/article-1-265-en.pdf 10.32598/jpr.8.3.856.1
22-257 2024-03-28 10.1002
Journal of Pediatrics Review J. Pediatr. Rev 2322-4398 2322-4401 10.32598 2020 8 3 The Chronic Intermittent Form of Isovaleric Acidemia With Staphylococcal Scalded Skin Syndrome: A Case Report and Literature Review Daniel Zamanfar danielzamanfar@ymail.com Elham Keyhanian Elhamkeyhanian@yahoo.com Mobin Ghazaiean dr.mobin.gh@gmail.com Somayeh Rostami Maskopaii somayehrostami14@yahoo.com Isovaleric Acidemia (IVA) is an autosomal recessive Inborne Error of Metabolism (IEM), i.e., caused by the mutation of isovaleric-CoA dehydrogenase. Two phenotypes of IVA are reported; acute and chronic. The case was a 3-year-old boy with chronic intermittent presentation. Elevated 3-hydroxybutyric acid and isovaleric glycine in urinary acid profile was reported. We also performed a brief review about the presented case; IVA in international databases for English language articles on children.  Several manners exist to screen IVA patients and the best one is GC-MS in urine analysis. The prognosis of the disease depends on the early interventions. Isovaleric acidemia Chronic phenotype Isovaleric-CoA dehydrogenase 2020 7 01 181 188 http://jpr.mazums.ac.ir/article-1-257-en.pdf 10.32598/jpr.8.3.48.2
22-253 2024-03-28 10.1002
Journal of Pediatrics Review J. Pediatr. Rev 2322-4398 2322-4401 10.32598 2020 8 3 Growth Modulation With Reconstruction Plate for Genu Valgum Deformity in Twins: A Case Report and Literature Review‌ Salman Ghaffari orthosalman@yahoo.com‏ Parastoo Mohammad amini Swallow1375@gmail.com Genu valgum is an angular deformity caused by several reasons, such as congenital syndromes, post-traumatic bone dysplasia, or an idiopathic form. It generates cosmetic problems, difficulties in function, and pain. Manipulating the growth plate by hemiepiphysiodesis with implants helps to achieve the correct alignment. We presented twin girls diagnosed with genu valgum deformity who were suffering from cosmetic problems and pain. We used growth modulation to temporarily arrest the growth plate. This procedure was followed by photographs and after 8 months, the implants were removed without having overcorrection. A brief literature review was also performed concerning the reported cases in the international databases, such as PubMed and Google Scholar on growth modulation for genu valgum deformity in twins. Twin girls with genu valgum deformities underwent hemiepiphysiodesis surgeries. We used reconstruction plates and 3.5 mm non-cannulated screws to fix both the distal femur and proximal tibia to temporarily arrest the growth plate. When we achieved the correct alignment the devices were removed. Growth modulation Twins Genu valgum Reconstruction plate 2020 7 01 189 194 http://jpr.mazums.ac.ir/article-1-253-en.pdf 10.32598/jpr.8.3.832.1
22-310 2024-03-28 10.1002
Journal of Pediatrics Review J. Pediatr. Rev 2322-4398 2322-4401 10.32598 2020 8 3 Abdominal Cocoon Syndrome in a Child With Intestinal Obstruction: A Case Report and Literature Review Nidhi Mahajan Mitali Agarwal Arti Khatri a.khatri2008@gmail.com Yousuf Mohsin Bari Siddiqui Mamta Sengar mamtasengar@gmail.com Abdominal cocoon syndrome or idiopathic Sclerosing Encapsulating Peritonitis (SEP) is an extremely uncommon cause of intestinal obstruction. Its etiology is explainable through numerous theories. An eleven-year-old girl referred to the pediatric surgery OPD with complaints of abdominal pain for the past two weeks and vomiting for two days. Her family history for tuberculosis was positive. On examination, the abdomen was distended and slightly firm on palpation. The X-ray of her abdomen revealed multiple air-fluid levels. The CECT of the abdomen indicated dilated abdomen, duodenum, and proximal bowel loops. Some trapped inter bowel free fluid was also observed. The clinical presentation of subacute intestinal obstruction and the radiological features suggested a differential diagnosis of tubercular peritonitis versus pseudomyxoma peritonei. The obstructive symptoms demonstrated that the patient underwent an explorative laparotomy. Preoperatively, a thin membranous sac was identified enclosing multiple dilated small bowel loops. The sac was released by blunt dissection and part of the sac was provided for histopathological examination. Based on clinical, histopathological, and radiological findings, a diagnosis of abdominal cocoon syndrome was determined. The postoperative follow-up period of 6 months was uneventful. We presented a rare case of primary sclerosing encapsulating peritonitis, also reported as abdominal cocoon syndrome. It is among the rare potentially devastating causes of intestinal obstruction in children. A very high index of suspicion is imperative to arrive at its pre-operative diagnosis alone by clinical and radiological findings. Cocoon Encapsulating Paediatric Peritonitis 2020 7 01 195 200 http://jpr.mazums.ac.ir/article-1-310-en.pdf 10.32598/jpr.8.3.845.2
22-238 2024-03-28 10.1002
Journal of Pediatrics Review J. Pediatr. Rev 2322-4398 2322-4401 10.32598 2020 8 3 The Relationship Between Serum and Cerebrospinal Fluid Concentrations of Zinc in Febrile Seizure Mohammadreza Salehi Omran Saleh Valiollahi salehvalielahi@yahoo.com Hadi Parsian Abbas Mosapour Ali Bijani Mohammad Pournasrollah Background: Febrile Seizure (FS) which has different causes, is the most prevalent seizure type in children. Studies supported the role of Zinc (Zn) in FS.  Objectives: The present study aimed to evaluate the serum and Cerebrospinal Fluid (CSF) Zn level in children with FS.  Methods: This cross-sectional study was performed on 50 patients with FS aged 6 months-6 years in Amirkola Children’s Hospital in 2013-2014. The required demographic and clinical data were recorded employing a checklist. The serum and CSF Zn levels were determined using Atomic Absorption Spectrophotometry (AAS) method. The collected data were analyzed in SPSS using the Chi-squared teste, Independent Samples t-test, and Pearson correlation coefficient. Results: The mean±SD age of the explored patients was 12.78±8.38 months and their mean±SD serum Zn level was equal to 0.68±0.62 µg/L. In total, 34(68%) of these 50 children presented Zn deficiency. The mean±SD CSF Zn level was measured as 33.29±11.84 µg/L. Moreover, the mean±SD CSF Zn level was equal to 37.71±10.82 and 31.21±11.87 in normal and abnormal serum Zn groups, respectively. In terms of mean CSF Zn level, there was no significant difference between the studied patients with healthy and decreased serum Zn level; (P=0.07). No significant difference was found between the demographic/clinical characteristics of the investigated patients with FS and normal/abnormal serum levels of Zn (P>0.05).  Conclusions: The obtained data revealed that a significant number of patients with FS had decreased serum Zn level; however, no association was detected between serum and CSF Zn concentration levels. Febrile seizure Seizures Zinc Epilepsy 2020 7 01 201 208 http://jpr.mazums.ac.ir/article-1-238-en.pdf 10.32598/jpr.8.3.696.2
22-333 2024-03-28 10.1002
Journal of Pediatrics Review J. Pediatr. Rev 2322-4398 2322-4401 10.32598 2020 8 3 Convalescent Plasma: An Old Trick for the Treatment of COVID-19 Reza Jafari Sajjad Ranjbar Kouchaksaraei Reza Farid Hosseini Mehrnaz Nayeb Alireza Ranjbar alireza.ranjbar@web.de This article has no abstract. Convalescent plasma Immunotherapy COVID-19 2020 7 01 209 210 http://jpr.mazums.ac.ir/article-1-333-en.pdf 10.32598/jpr.8.3.270.1