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1- 1 Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran 2 Students' Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
2- 3 Department of Biostatistics and Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran 4 Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran , awat_feiz@hlth.mui.ac.ir
3- 1 Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran and 4 Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
4- 1 Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract:   (322 Views)
Background and objective: Metabolic syndrome (MetS) predisposes to a variety of chronic diseases. This study, for the first time, aimed to assess the effects of fermented camel milk (FCM), a functional dairy food, on obesity measures and blood pressure of adolescents with MetS.
Methods: The study was conducted as a crossover randomized double-blind trial. It enrolled overweight/obese adolescents, aged 11-18 years, with the criteria of MetS. We randomly assigned participants to receive FCM 250 cc per day for 8 weeks, a 4-week washout, and then diluted cow's yogurt (DCY) 250 cc per day for 8 weeks, or the reverse sequence. General and abdominal obesity measures consisting of weight, body mass index (BMI), BMI z-score, waist circumference (WC), hip circumference (HC) and waist to height ratio and systolic and diastolic blood pressure (SBP, DBP) were measured before and after each of the four periods. A three-day food record and physical activity questionnaire were completed before each period.  Statistical analyses were done using Minitab and SPSS software considering the significance level of 0.05. 
Results: Twenty-four participants with a mean (SD) age of 13.77 (1.87) years (range: 10.45-16.25) (58% girls) completed the study. It resulted in non-significant lesser mean increase, or mean decrease in weight (-0.67 kg (95% CI: -1.97; 0.61); p= 0.28), BMI (-0.10 kg/m2 (95% CI: -0.65; 0.45); p= 0.70), BMI z-score (-0.06 (95% CI: -0.33; 0.19); p= 0.59), WC (-1.10 cm (95% CI: -3.22; 1.01); p= 0.29) and HC (-0.12 cm (95% CI: -2.04; 1.79); p= 0.89) by FCM consumption in comparison to DCY. It resulted in non-significant mean reduction in DBP (-4.45 mmHg (95% CI: -10.04; 1.12); p= 0.11) and SBP (-5.52 mmHg (95% CI: -12.82; 1.78); p=0.13) with significant carry-over effect as well.
Conclusion: According to some positive impacts of FCM on obesity measures and blood pressure, we suggest conducting further studies to validate the clinical impacts of fermented camel milk.
Full-Text [PDF 651 kb]   (88 Downloads)    
Type of Study: Original Article |
Received: 2018/01/27 | Accepted: 2018/06/30 | Published: 2018/07/14

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