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1- PhD student 1 Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran 2 Students' Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
2- Asssociate Prof. 3 Department of Biostatistics and Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran 4 Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran , awat_feiz@hlth.mui.ac.ir
3- Professor 1 Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran and 4 Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
4- Msc 1 Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
5- Bsc 1 Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
6- Professor 1 Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract:   (216 Views)
Background and objective
Metabolic syndrome (MetS) predisposes to a variety of chronic diseases. This study, for the first time, aimed to assess the effects of fermented camel milk (FCM), a functional dairy food, on obesity measures and blood pressure of adolescents with MetS.
Methods
The study was conducted as a crossover randomized double-blind trial. It enrolled overweight/obese adolescents, aged 11-18 years, with the criteria of MetS. We randomly assigned participants to receive FCM 250 cc per day for 8 weeks, a 4-week washout, and then diluted cow's yogurt (DCY) 250 cc per day for 8 weeks, or the reverse sequence. General and abdominal obesity measures consisting of weight, body mass index (BMI), BMI z-score, waist circumference (WC), hip circumference (HC) and waist to height ratio and systolic and diastolic blood pressure (SBP, DBP) were measured before and after each of the four periods. A three-day food record and physical activity questionnaire were completed before each period.  Statistical analyses were done using Minitab and SPSS software considering the significance level of 0.05. 
Results
Twenty-four participants with a mean (SD) age of 13.77 (1.87) years (range: 10.45-16.25) (58% girls) completed the study. It resulted in non-significant lesser mean increase, or mean decrease in weight (-0.67 kg (95% CI: -1.97; 0.61); p= 0.28), BMI (-0.10 kg/m2 (95% CI: -0.65; 0.45); p= 0.70), BMI z-score (-0.06 (95% CI: -0.33; 0.19); p= 0.59), WC (-1.10 cm (95% CI: -3.22; 1.01); p= 0.29) and HC (-0.12 cm (95% CI: -2.04; 1.79); p= 0.89) by FCM consumption in comparison to DCY. It resulted in non-significant mean reduction in DBP (-4.45 mmHg (95% CI: -10.04; 1.12); p= 0.11) and SBP (-5.52 mmHg (95% CI: -12.82; 1.78); p=0.13) with significant carry-over effect as well.
Conclusion
According to some positive impacts of FCM on obesity measures and blood pressure, we suggest conducting further studies to validate the clinical impacts of fermented camel milk.
Full-Text [PDF 651 kb]   (65 Downloads)    
Type of Study: Original Article |
Received: 2018/01/27 | Accepted: 2018/06/30 | Published: 2018/07/14

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