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1- Department of Nutrition, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
2- Department of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
3- Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
4- Environment Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
5- Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran , m.khoshhali@yahoo.com
Abstract:   (681 Views)
Context: Physical environment and in particular, air pollution might cause long-term adverse effects in programming child growth and development and higher risk of NCDs later in life
Objective: This study aims to provide an overview of human studies on the association of exposure to ambient particulate matter (PM) and childhood obesity.
Data Sources: We systematically searched human studies available till March 2018 in PubMed, Scopus, Ovid, ISI Web of Science, Cochrane library, and Google Scholar databases.
Study Selection: All studies that explored the association between PM exposure and childhood obesity were assessed in the present study and 5 studies was included in meta-analysis.
Data Extraction: The data extraction and quality assessment of the studies were performed by two independent individuals. STROBE statements checklist was used for quality assessment of papers.
Results: The pooled analysis of PM exposure was significantly associated with increased BMI (Fisher-z=0.028; 95% CI(0.017, 0.038)) using the fixed effects model. As significant high heterogeneity of the included studies on PM was observed (I2=94.4%; P<0.001), a random effect model was used. PM exposure was associated with increased BMI (Fisher-z=0.022; 95%CI (-0.057, 0.102)); the overall effect size was not significant and heterogeneity of the included studies was as same fixed effect model. Our findings on the significant association between PM10 exposure and the increased BMI(r=0.034; 95%CI (0.007,0.061)) without heterogeneity(I 2=16.6%,P =0.274)in the studies with PM10suggest that the PM type might account for the heterogeneity among the studies.
Conclusion: The findings indicate that exposure to ambient PM10 might have significant effects on childhood obesity.

 
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Type of Study: Meta-analysis Review | Subject: Pediatric Endocrinology
Received: 2018/10/10 | Accepted: 2019/03/9

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