Volume 8, Issue 2 (In Press 2020)                   J. Pediatr. Rev 2020, 8(2): 3-3 | Back to browse issues page

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Ahmadzadeh-Amiri A, Alaee A, Ahmadzadeh-Amiri A. Neuroimaging in Pediatric Optic Neuritis: A Narrative Review. J. Pediatr. Rev. 2020; 8 (2) :3-3
URL: http://jpr.mazums.ac.ir/article-1-245-en.html
1- Department of Pediatric, Bahrami Children’s Hospital, Tehran University of Medical Sciences, Tehran, IR Iran
2- Department of Radiology, Mazandaran University of Medical Sciences, Sari, IR Iran, email:
3- Department of Ophthalmology, Clinical Research Development Unit of Bu-Ali Sina Hospital, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, IR Iran , Ahmadzdh@yahoo.com
Abstract:   (578 Views)
Context: Pediatric optic neuritis can occur in isolation or in association with neuroinflammatory disorders. Abnormal orbital and cranial Magnetic Resonance Imaging were reviewed in literature diagnosed as Pediatric Optic Neuritis primarily presented with visual problems.
Evidence Acquisition: A PubMed literature search was accomplished using the following search terms; Neuroimaging, Pediatric, Optic Neuritis, Multiple Sclerosis, and Magnetic Resonance Imaging.
Results: Poorly demarcated changes in white and/or gray matter, well-demarcated white matter changes, confluent lesions in white matter, and nonspecific small lesions or nothing in certain regions of the brain are the most common patterns of children with optic neuritis. Optic nerve lesions can be revealed by the thin fat suppression imaging technique. Contrast-enhanced sequences, especially by short tau inversion recovery, allow differentiation of particular high-signal intensity foci in the optic nerve and newly formed active lesions from inactive lesions.
Conclusion: Brain imaging should be performed in all patients, if possible, during the following two weeks after the initial diagnosis. The cranial neuroimaging can predict multiple sclerosis development in pediatric patients with demyelinating brain lesions.
Full-Text [PDF 492 kb]   (209 Downloads)    
Type of Study: Narrative Review | Subject: Radiology
Received: 2019/06/12 | Accepted: 2019/08/28 | Published: 2019/12/30

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