Volume 9, Issue 1 (In Press 2021)                   J. Pediatr. Rev 2021, 9(1): 0-0 | Back to browse issues page


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Rezai M S, Shahbaznejad L. COVID-19 in Children Managed Without Antiviral Drugs. J. Pediatr. Rev. 2021; 9 (1)
URL: http://jpr.mazums.ac.ir/article-1-378-en.html
1- Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.
2- Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran. , leilashahbaznezhad@gmail.com
Abstract:   (189 Views)
Coronavirus disease 2019 (COVID-19) manifests with various symptoms and complications, but it generally presents with milder symptoms in children. There are different published guidelines about the management of COVID-19 in children. We share our experiences in managing moderate to severe presentations and complications of the disease in a tertiary children’s hospital in the north of Iran. Our recommendation for the management of MIS-C (multisystem inflammatory syndrome in children) patients in the presence of coronary artery involvement starts with 2 g/kg Intravenous immunoglobulin (IVIG) and in resistant cases, or the presence of myocarditis methylprednisolone pulse therapy in three consecutive days. Pulse therapy is also recommended in cases without coronary artery involvement as the first step of treatment.  Other essential conservative management strategies are albumin replacement, hemoglobin monitoring, inotropes, meticulous use of antibiotics, and anticoagulants. All cases with MIS-C must be admitted to the pediatric intensive care unit. Moderate to severe cases are managed with supportive care, including hydration, vitamin D, vitamin C, zinc, and, if indicated, supplementary oxygen, and antibiotics. The most important part of the management of MIS-C is close monitoring of cardiovascular function, supportive care, and administration of corticosteroid and IVIG.
Full-Text [DOCX 17 kb]   (30 Downloads)    
Type of Study: Letter to the Editor | Subject: Infectious Diseases
Received: 2020/12/20 | Accepted: 2021/01/21 | Published: 2021/01/21

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