Volume 10, Issue 3 (In Press 2022)                   J. Pediatr. Rev 2022, 10(3): 2-2 | Back to browse issues page

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Fakhri M, Farhadi R, Yousefi S S, Moosazadeh M, Ramezanpour M, Azadbakht M. The Effect of Dextrose Gel on the Prevention and Treatment of Neonatal Hypoglycemia: A Systematic Review and Meta-Analysis. J. Pediatr. Rev. 2022; 10 (3) :2-2
URL: http://jpr.mazums.ac.ir/article-1-465-en.html
The Effect of Dextrose Gel on the Prevention and Treatment of Neonatal Hypoglycemia: A Systematic Review and Meta-Analysis
Moloud Fakhri 1, Roya Farhadi2 , Seyde Sedighe Yousefi2 , Mahmood Moosazadeh2 , Melina Ramezanpour2 , Mohammad Azadbakht2
1- Mazandaran University of Medical Sciences, Mazandaran, Iran. , mmfir@yahoo.com
2- Mazandaran University of Medical Sciences, Mazandaran, Iran.
Abstract:   (201 Views)
Neonatal hypoglycemia is one of the major complications in neonatal wards, requiring rapid diagnosis and treatment to prevent its complications. Dextrose gel is used as a cheap and safe choice. Thus, the present systematic review and meta-analysis aimed to investigate the effect of oral dextrose gel in the prevention and treatment of neonatal hypoglycemia. To find the relevant articles, the domestic databases, including Barekat Gostar, SID, Magiran, IranDoc, and international databases, including PubMed, Scopus, Web of Science, Cochrane, and Google Scholar search engine were searched with standard keywords. Data were analyzed using STATA 14 software, and P-value<0.05 were considered significant. In the 9 study articles with a sample size of 8755 neonates, the mean neonatal weight ranged between 2890 to 3669 grams. 61% of the neonates were born through normal vaginal delivery, 16% were low birth weight (below 2500 grams), 16% had high birth weight (above 4500 grams), 51% had diabetic mothers, 20% were premature, and 88% were singleton. Oral dextrose gel reduced the risk of neonatal hypoglycemia by OR=0.83 (95% CI: 0.75-0.93). Though, neonatal hypoglycemia treatment with oral dextrose gel had an OR=0.78 (95% CI: 0.57-1.07) which was not statistically significant. Oral dextrose gel was effective in neonatal hypoglycemia prevention.
 
Keywords: Dextrose gel, Prevention, therapy, Hypoglycemia, “Infant, Newborn”
     
Type of Study: Meta-analysis Review | Subject: Neonatology
Received: 2022/04/9 | Accepted: 2022/05/31 | Published: 2022/10/17
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