Mon, Sep 29, 2025
Volume 13, Issue 3 (7-2025)
J. Pediatr. Rev 2025, 13(3): 183-192 |
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Kalejahi P, Noorazar S G. Magnesium Status and Supplementation in Children With Attention-deficit/Hyperactivity Disorder: A Systematic Review. J. Pediatr. Rev 2025; 13 (3) :183-192
URL: http://jpr.mazums.ac.ir/article-1-620-en.html
URL: http://jpr.mazums.ac.ir/article-1-620-en.html
1- Research Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, Iran. , parinaz.kalejahi@gmail.com
2- Research Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
2- Research Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Abstract: (278 Views)
Background: Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental condition that can have major effects on the affected individual’s personal and social life. Complementary treatments, including nutritional supplements, can help improve the symptoms of patients with ADHD. Therefore, this review study investigated magnesium deficiency in children with ADHD and the effectiveness of this mineral supplement.
Methods: This paper systematically reviewed the literature available in Google Scholar, PubMed, and Scopus databases. Studies focusing on children with ADHD published in English were selected without any time limitations, up to December 2023. From a comprehensive review of 1,115 publications, eight articles were carefully selected for inclusion in the study.
Results: Selected descriptive studies have demonstrated a correlation between ADHD and reduced levels of magnesium in children’s serum and hair compared to their healthy counterparts. Furthermore, magnesium supplementation is an effective means of mitigating the symptoms associated with this disorder.
Conclusions: According to recent research, magnesium micronutrient has shown potential in alleviating the symptoms associated with ADHD. This is attributed to its pivotal role in the central nervous system. Given its significance in regulating neurotransmitters and synaptic plasticity, magnesium is a valuable addition to the existing treatment options for ADHD. Further studies are warranted to fully elucidate its efficacy and potential side effects. Nonetheless, the findings thus far are promising and merit consideration by healthcare professionals.
Methods: This paper systematically reviewed the literature available in Google Scholar, PubMed, and Scopus databases. Studies focusing on children with ADHD published in English were selected without any time limitations, up to December 2023. From a comprehensive review of 1,115 publications, eight articles were carefully selected for inclusion in the study.
Results: Selected descriptive studies have demonstrated a correlation between ADHD and reduced levels of magnesium in children’s serum and hair compared to their healthy counterparts. Furthermore, magnesium supplementation is an effective means of mitigating the symptoms associated with this disorder.
Conclusions: According to recent research, magnesium micronutrient has shown potential in alleviating the symptoms associated with ADHD. This is attributed to its pivotal role in the central nervous system. Given its significance in regulating neurotransmitters and synaptic plasticity, magnesium is a valuable addition to the existing treatment options for ADHD. Further studies are warranted to fully elucidate its efficacy and potential side effects. Nonetheless, the findings thus far are promising and merit consideration by healthcare professionals.
Type of Study: Systematic Review |
Subject:
Pediatric Neurology
Received: 2024/04/16 | Accepted: 2025/07/19 | Published: 2025/07/19
Received: 2024/04/16 | Accepted: 2025/07/19 | Published: 2025/07/19
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