جمعه 13 تیر 1404
دوره 11، شماره 2 - ( 1-1402 )
جلد 11 شماره 2 صفحات 134-125 |
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Farhadi R. Hepatobiliary Involvement in Neonates With COVID-19 Infection: A Narrative Review. J. Pediatr. Rev 2023; 11 (2) :125-134
URL: http://jpr.mazums.ac.ir/article-1-498-fa.html
URL: http://jpr.mazums.ac.ir/article-1-498-fa.html
Hepatobiliary Involvement in Neonates With COVID-19 Infection: A Narrative Review. Journal of Pediatrics Review. 1402; 11 (2) :125-134
چکیده: (2104 مشاهده)
Background: The most common symptoms in neonates with severe COVID-19 infection have been respiratory problems. The virus may adversely affect organs such as the liver.
Methods: Studies focusing solely on liver involvement in newborns with COVID-19 infection were searched in Pubmed, Scopus, and Google Scholar databases. Eight studies were finally reviewed.
Results: Direct viral invasion (COVID-19-induced hepatitis or systemic inflammatory response) and drug-induced may contribute to liver damage in neonates. SARS-CoV-2 may be the latest spark in toxoplasmosis, other agents, rubella, cytomegalovirus, herpes infections, and fetal liver involvement may be induced by transplacental transmission.
Conclusions: Hepatic dysfunction is infrequent but important in neonates with COVID-19 infection and the mechanism of liver damage associated with COVID-19 may differ from that in adults.
Methods: Studies focusing solely on liver involvement in newborns with COVID-19 infection were searched in Pubmed, Scopus, and Google Scholar databases. Eight studies were finally reviewed.
Results: Direct viral invasion (COVID-19-induced hepatitis or systemic inflammatory response) and drug-induced may contribute to liver damage in neonates. SARS-CoV-2 may be the latest spark in toxoplasmosis, other agents, rubella, cytomegalovirus, herpes infections, and fetal liver involvement may be induced by transplacental transmission.
Conclusions: Hepatic dysfunction is infrequent but important in neonates with COVID-19 infection and the mechanism of liver damage associated with COVID-19 may differ from that in adults.
نوع مطالعه: Review Article |
موضوع مقاله:
نوزادان
دریافت: 1401/7/14 | پذیرش: 1401/11/1 | انتشار: 1402/1/12
دریافت: 1401/7/14 | پذیرش: 1401/11/1 | انتشار: 1402/1/12
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