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Saleh F, Karimi Rouzbahani A, Naghmehsanj Z, Molavi M A. Isolated Unilateral Orbital Myeloid Sarcoma (an Isolated Extra Medullary Myeloid Leukemia): A Case Report. J. Pediatr. Rev 2026; 14 (2) :207-212
URL: http://jpr.mazums.ac.ir/article-1-623-fa.html

Background: Myeloid sarcoma (MS) is a rare condition characterized by extramedullary proliferation of myeloid blasts in various tissues, with or without bone marrow involvement. It is strongly associated with acute myeloid leukemia (AML), chronic myeloid leukemia (CML), and myelodysplastic syndromes (MDS), and is often misdiagnosed as lymphoma. 
Case Presentation: We herein report a case of isolated unilateral orbital MS presenting as extramedullary infiltration of myeloid blasts without bone marrow involvement in a patient from Iran.
Conclusions: Patients with isolated MS who receive AML-type chemotherapy may experience more favorable outcomes compared to patients who have AML with or without associated MS.