چهارشنبه 20 تیر 1403
دوره 11، شماره 3 - ( 4-1402 )
جلد 11 شماره 3 صفحات 244-231 |
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Rezai M S, Rostami-Maskopaee F, Navaeifar M R, Hajialibeig A, Gooran M, Haghighi Aski B, et al . Multisystem Inflammatory Syndrome Mortality Following COVID-19 in Iranian Children: A Case Series and Literature Review. J. Pediatr. Rev 2023; 11 (3) :231-244
URL: http://jpr.mazums.ac.ir/article-1-535-fa.html
URL: http://jpr.mazums.ac.ir/article-1-535-fa.html
Multisystem Inflammatory Syndrome Mortality Following COVID-19 in Iranian Children: A Case Series and Literature Review. Journal of Pediatrics Review. 1402; 11 (3) :231-244
چکیده: (969 مشاهده)
Background: Children generally are less contaminated by COVID-19 than other age groups, but multisystem inflammatory syndrome-children (MIS-C) can cause severe outcomes in some children. The information about MIS-C patient mortality is limited, and the cause of mortality may vary by geographical region. Therefore, we performed this case series study to report the clinical features and treatment of MIS-C patients associated with COVID-19 who died in selected referral hospitals in Iran.
Case Presentation: We presented 9 cases of deceased MIS-C patients hospitalized from March 2020 to September 2021. The median age of deceased patients was 89 months (interquartile range: 8-162 mo). Five patients (55%) were male. The COVID-19 reverse transcription polymerase chain reaction (PCR) or serology test was positive in 7 children (77%). About 80% of the patients had comorbidities, most commonly obesity. All the patients were febrile at admission, and 77.78% had a fever for over 5 days. Respiratory, cardiac, and gastrointestinal signs were the most common. On admission, 6 patients were transferred to the pediatric intensive care unit. All patients received intravenous immunoglobulin and steroids.
Conclusions: The most common organ failure was lung, heart, liver, and kidney, but the main cause of death was cardiopulmonary failure. Early diagnosis and management of MIS-C are necessary to prevent severe complications and death.
Case Presentation: We presented 9 cases of deceased MIS-C patients hospitalized from March 2020 to September 2021. The median age of deceased patients was 89 months (interquartile range: 8-162 mo). Five patients (55%) were male. The COVID-19 reverse transcription polymerase chain reaction (PCR) or serology test was positive in 7 children (77%). About 80% of the patients had comorbidities, most commonly obesity. All the patients were febrile at admission, and 77.78% had a fever for over 5 days. Respiratory, cardiac, and gastrointestinal signs were the most common. On admission, 6 patients were transferred to the pediatric intensive care unit. All patients received intravenous immunoglobulin and steroids.
Conclusions: The most common organ failure was lung, heart, liver, and kidney, but the main cause of death was cardiopulmonary failure. Early diagnosis and management of MIS-C are necessary to prevent severe complications and death.
نوع مطالعه: Case & Review |
دریافت: 1402/2/10 | پذیرش: 1402/3/22 | انتشار: 1402/4/10
دریافت: 1402/2/10 | پذیرش: 1402/3/22 | انتشار: 1402/4/10
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