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Altan H, Cosgun A, Altan A. Cow’s Milk Protein Allergy in Pediatric Dentistry: A Narrative Review. J. Pediatr. Rev. 2019; 7 (1) :11-16
URL: http://jpr.mazums.ac.ir/article-1-161-en.html
1- Department of Pediatric Dentistry, Faculty of Dentistry, Gaziosmanpaşa University, Tokat, Turkey.
2- Department of Pediatric Dentistry, Faculty of Dentistry, Mustafa Kemal University, Antakya, Turkey.
3- Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Gaziosmanpaşa University, Tokat, Turkey. , dt.ahmetaltan@gmail.com
Abstract:   (6906 Views)
Context: Immunological reactions against proteins found in cow’s milk (casein and whey proteins) are called Cow’s Milk Protein Allergy (CMPA). CMPA has systemic as well as oral symptoms. Also, any casein-containing products used for preventive and therapeutic purposes in dentistry may trigger this allergy. The objective of this compilation is to reveal the importance of CMPA in dentistry by adhering to the literature. 
Evidence Acquisition: A literature search was done using PubMed, with focus on articles published in the last 10 years. Searched terms included the following: cow’s milk protein allergy, child, pathogenesis, prevention, management, and dentistry.
Results: Oral allergy syndrome and dental erosion caused by gastroesophageal reflux were observed in 40% of patients with CMPA that were detected by the dentists. 
Conclusions: Pediatric dentists should be aware of CMPA and pediatricians should be given support in definitive diagnosis of CMPA.
Full-Text [PDF 568 kb]   (2665 Downloads) |   |   Full-Text (HTML)  (4615 Views)  
Type of Study: Narrative Review |
Received: 2018/01/19 | Accepted: 2018/02/25 | Published: 2019/01/1

1. Cohen SG, Saavedra-Delgado AM. Through the centuries with food and drink, for better or worse. Allergy and Asthma Proceedings. 1989; 10(4):281-90. [DOI:10.2500/108854189778960009] [PMID] [DOI:10.2500/108854189778960009]
2. Özçeker D, Tamay Z. [Approach to cow milk allergy in children (Turkish)]. Istanbul Science University Florence Nightingale Medical Journal. 2015; 1(2):108-14. [DOI:10.5606/fng.btd.2015.021] [DOI:10.5606/fng.btd.2015.021]
3. Koca T, Akçam M. Cow's-milk protein allergy. Dicle Medical Journal. 2015; 42(2):268-73.
4. Businco L, Benincori N, Cantani A. Epidemiology, incidence and clinical aspects of food allergy. Annals of Allergy. 1984; 53(6 Pt 2):615-22. [PMID] [PMID]
5. Buttriss J. Adverse reactions to food: The report of a British nutrition foundation task force. Hoboken, New Jersey: Wiley-Blackwell; 2001. [PMID] [DOI:10.1002/9780470698792] [PMID]
6. Köksal G, Gökmen H. Nutritional Therapy in Pediatric Diseases. Ankara: Hatiboglu Publications. 2000; 251-255.
7. Exl BM, Fritsché R. Cow's milk protein allergy and possible means for its prevention. Nutrition. 2001; 17(7):642-51. [DOI:10.1016/S0899-9007(01)00566-4] [DOI:10.1016/S0899-9007(01)00566-4]
8. Sicherer SH. Epidemiology of food allergy. Journal of Allergy and Clinical Immunology. 2011; 127(3):594-602. [DOI:10.1016/j.jaci.2010.11.044] [PMID] [DOI:10.1016/j.jaci.2010.11.044]
9. Altıntaş DU. [Cow Milk Allergy (Turkish)]. Turkiye Klinikleri Journal of Allergy & Asthma. 2003; 5(3):164-7.
10. Schade RP, Van Ieperen-Van Dijk AG, Versluis C, Van Reijsen FC, Kimpen JL, Bruijnzeel-Koomen CA, et al. Cell-surface expression of CD25, CD26, and CD30 by allergen-specific T cells is intrinsically different in cow's milk allergy. The Journal of Allergy and Clinical Immunology. 2002; 109(2):357-62. [DOI:10.1067/mai.2002.121457] [PMID] [DOI:10.1067/mai.2002.121457]
11. Altintaş D, Güneşer S, Evliyaoglu N, Yüksel B, Atici A, Serbest M. A prospective study of cow's milk allergy in Turkish infants. Acta Pædiatrica. 1995; 84(11):1320-1. [DOI:10.1111/j.1651-2227.1995.tb13559.x] [DOI:10.1111/j.1651-2227.1995.tb13559.x]
12. Arıcan Ö, OY H. Food allergy. Kartal Training and Research Hospital Medical Journal. 2002; 2: 142-146.
13. Sapan N, Demir E, Tamay Z, Akçakaya N, Güler N, Yazıcıoğlu M, et al. Guideline for diagnosis and treament of food allergy in children by "academia of pediatric allergy and asthma society" . Turkısh Archives of Pediatrics. 2013; 48(4):270-4. [DOI:10.4274/tpa.2029] [DOI:10.4274/tpa.2029]
14. Sicherer SH, Sampson HA. Food allergy. The Journal of allergy and clinical immunology. 2010; 125(2 Suppl 2):S116-25. [DOI:10.1016/j.jaci.2009.08.028] [PMID] [DOI:10.1016/j.jaci.2009.08.028]
15. Adkinson Jr NF, Bochner BS, Burks AW, Busse WW, Holgate ST, Lemanske RF, et al. Middleton's allergy E-Book: Principles and practice. Amsterdam: Elsevier Health Sciences; 2013.
16. Halken S. Prevention of food allergy. Environmental Toxicology and Pharmacology. 1997; 4(1-2):149-56. [DOI:10.1016/S1382-6689(97)10056-4] [DOI:10.1016/S1382-6689(97)10056-4]
17. Renz H, Herz U. The bidirectional capacity of bacterial antigens to modulate allergy and asthma. The European Respiratory Journal. 2002; 19(1):158-71. [DOI:10.1183/09031936.02.00254202] [PMID] [DOI:10.1183/09031936.02.00254202]
18. Öztürk UD, Besler HT. [Food allergies (Turkish)]. Ankara: Ministry of Health publications; 2012.
19. Ortolani C, Ispano M, Scibilia J, Pastorello EA. Introducing chemists to food allergy. Allergy. 2001; 56:5-8.[DOI:10.1111/j.1398-9995.2001.00901.x] [PMID] [DOI:10.1111/j.1398-9995.2001.00901.x]
20. Fiocchi A, Schunemann HJ, Brozek J, Restani P, Beyer K, Troncone R, et al. Diagnosis and Rationale for Action Against Cow's Milk Allergy (DRACMA): A summary report. The Journal of Allergy and Cinical Immunology. 2010; 126(6):1119-28. [DOI:10.1016/j.jaci.2010.10.011] [PMID] [DOI:10.1016/j.jaci.2010.10.011]
21. Wal JM. Cow's milk allergens. Allergy. 1998; 53(11):1013-22. [DOI:10.1111/j.1398-9995.1998.tb03811.x] [PMID] [DOI:10.1111/j.1398-9995.1998.tb03811.x]
22. Ortolani C, Ispano M, Scibilia J. Introducing chemists to food allergy. Allergy. 2001; 56(s67):5-8. [DOI:10.1111/j.1398-9995.2001.00901.x] [PMID] [DOI:10.1111/j.1398-9995.2001.00901.x]
23. Chatchatee P, Järvinen KM, Bardina L, Beyer K, Sampson HA. Identification of IgE-and IgG-binding epitopes on αs1-casein: Differences in patients with persistent and transient cow's milk allergy. Journal of Allergy and Clinical Immunology. 2001; 107(2):379-83. [DOI:10.1067/mai.2001.112372] [PMID] [DOI:10.1067/mai.2001.112372]
24. Goldman AS, Anderson DW, Sellers WA, Saperstein S, Kniker WT, Halpern SR. Milk allergy: I. Oral challenge with milk and isolated milk proteins in allergic children. Pediatrics. 1963; 32:425-43. [PMID] [PMID]
25. Reynolds EC. Remineralization of enamel subsurface lesions by casein phosphopeptide-stabilized calcium phosphate solutions. Journal of Dental Research. 1997; 76(9):1587-95. [DOI:10.1177/00220345970760091101] [PMID] [DOI:10.1177/00220345970760091101]
26. Cross KJ, Huq NL, Bicknell W, Reynolds EC. Cation-dependent structural features of beta-casein-(1-25). The Biochemical Journal. 2001; 356(Pt 1):277-86. [DOI:10.1042/0264-6021:3560277] [PMID] [PMCID] [DOI:10.1042/0264-6021:3560277]
27. Restani P, Velona T, Plebani A, Ugazio AG, Poiesi C, Muraro A, et al. Evaluation by SDS-PAGE and immunoblotting of residual antigenicity in hydrolysed protein formulas. Clinical and experimental allergy. Journal of the British Society for Allergy and Clinical Immunology. 1995; 25(7):651-8. [DOI:10.1111/j.1365-2222.1995.tb01113.x] [PMID] [DOI:10.1111/j.1365-2222.1995.tb01113.x]
28. Çehreli SB. [Early childhood caries and associated factors (Turkish)]. Turkiye Klinikleri Journal of Pediatric Dentistry-Special Topics (E-Journal). 2015; 1(1):55-9.
29. Demirbağ BC, Tanır MK, Kuğuoğlu S. [Oral Thrush Infection in Infants between 1-12 Months and Approaches the Traditional used by Mothers for Treatment (Turkish)]. Electronic Journal of Vocational Colleges. 2012; 2(1):136-44.
30. Çetinkaya F. [Child and allergy (Turkish)]. 2nd ed. Istanbul: UCB Pharma; 1998.
31. Ortolani C, Ispano M, Pastorello EA, Ansaloni R, Magri GC. Comparison of results of skin prick tests (with fresh foods and commercial food extracts) and RAST in 100 patients with oral allergy syndrome. The Journal of Allergy and Clinical Immunology. 1989; 83(3):683-90. [DOI:10.1016/0091-6749(89)90083-3] [DOI:10.1016/0091-6749(89)90083-3]
32. Fiocchi A, Schünemann HJ, Brozek J, Restani P, Beyer K, Troncone R, et al. Diagnosis and rationale for action against cow's milk allergy (DRACMA): a summary report. Journal of Allergy and clinical immunology. 2010; 126(6):1119-28. [DOI:10.1016/j.jaci.2010.10.011] [DOI:10.1016/j.jaci.2010.10.011]
33. De Oliveira PAD, Paiva SM, De Abreu MHNG, Auad SM. Dental erosion in children with gastroesophageal reflux disease. Paediatric Dentistry. 2016; 38(3):246-50. [PMID] [PMID]
34. Barron RP, Carmichael RP, Marcon MA, Sandor G. Dental erosion in gastroesophageal reflux disease. Journal of Canadian Dental Association. 2003; 69(2):84-9. [PMID] [PMID]
35. Dahshan A, Patel H, Delaney J, Wuerth A, Thomas R, Tolia V. Gastroesophageal reflux disease and dental erosion in children. Journal of Pediatrics. 2002; 140(4):474-8. [DOI:10.1067/mpd.2002.123285] [PMID] [DOI:10.1067/mpd.2002.123285]
36. Di Fede O, Di Liberto C, Occhipinti G, Vigneri S, Lo Russo L, Fedele S, et al. Oral manifestations in patients with gastro-oesophageal reflux disease: A single-center case–control study. Journal of Oral Pathology & Medicine. 2008; 37(6):336-40. [DOI:10.1111/j.1600-0714.2008.00646.x] [PMID] [DOI:10.1111/j.1600-0714.2008.00646.x]
37. Sari ME, Koyutürk AE. [Relationship to erosion of primary and permanent teeth of gastroosefageal reflux in children: A literature review (Turkish)]. Cumhuriyet Dental Journal. 2010; 13(2):81-5.
38. Jarvinen KM, Beyer K, Vila L, Chatchatee P, Busse PJ, Sampson HA. B-cell epitopes as a screening instrument for persistent cow's milk allergy. The Journal of Allergy and Clinical Immunology. 2002; 110(2):293-7. [DOI:10.1067/mai.2002.126080] [PMID] [DOI:10.1067/mai.2002.126080]
39. Pai D, Bhat SS, Taranath A, Sargod S, Pai VM. Use of laser fluorescence and scanning electron microscope to evaluate remineralization of incipient enamel lesions remineralized by topical application of casein phospho peptide amorphous calcium phosphate (CPP-aCP) containing cream. The Journal of Clinical Pediatric Dentistry. 2008; 32(3):201-6. [DOI:10.17796/jcpd.32.3.d083470201h58m13] [PMID] [DOI:10.17796/jcpd.32.3.d083470201h58m13]
40. Silva KG, Pedrini D, Delbem AC, Ferreira L, Cannon M. In situ evaluation of the remineralizing capacity of pit and fissure sealants containing amorphous calcium phosphate and/or fluoride. Acta Odontologica Scandinavica. 2010; 68(1):11-8. [DOI:10.3109/00016350903260264] [PMID] [DOI:10.3109/00016350903260264]
41. Ardu S, Castioni NV, Benbachir-Hassani N, Krejci I. Minimally invasive treatment of white spot enamel lesions. Quintessence International. 2007; 38(8):633-6. [PMID] [PMID]

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