Volume 7, Issue 2 (4-2019)                   J. Pediatr. Rev 2019, 7(2): 77-88 | Back to browse issues page

XML Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Boskabadi H, Zakerihamidi M. Evaluation of Maternal Risk Factors, Delivery, and Neonatal Outcomes of Premature Rupture of Membrane: A Systematic Review Study. J. Pediatr. Rev 2019; 7 (2) :77-88
URL: http://jpr.mazums.ac.ir/article-1-170-en.html
1- Department of Pediatrics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
2- Department of Midwifery, School of Medical Sciences, Tonekabon Branch, Islamic Azad University, Tonekabon, Iran. , maryamzakerihamidi@yahoo.co.nz
Abstract:   (11640 Views)
Context: Premature rupture of membrane is a serious complication in pregnancy and responsible for one third of preterm labors associated with the neonatal and delivery outcomes. 
Objective: The current study aimed at investigating the risk factors of premature rupture of membrane on delivery and neonatal implications.
Data Sources: The articles on the databases, including PubMed, Cochrane Library, ISI and Google Scholar up to 2017 were searched to conduct the current study. The keywords used were “premature rupture of membrane”, “neonatal,” “risk factors”, “maternal”, and “delivery”.
Study Selection: The inclusion criteria were articles on the relationship between maternal risk factors and Premature Rupture of Membrane (PROM), neonatal outcomes of PROM, the delivery outcomes of PROM, the study of mothers and infants, English and Persian language articles, and sufficient information on the PROM. The articles investigating amniotomy or the ones that only their abstracts were available were excluded from the study.
Data Extraction: The data extracted from the above mentioned databases were fed with the following titles in the Excel software: Authors’ names and surnames, year of study, type of study, place of study, case group, control group, maternal risk factors, delivery outcomes, neonatal outcomes of PROM, and the results of the study.
Results: Out of 90 articles, 15 articles were finalized including one prospective study, five cross-sectional papers, six retrospective articles, and three historical cohort studies. Maternal risk factors included age; parity; education; occupation; diabetes; blood pressure; cervical length along with abortion history; history of infection, upper urinary tract infection, and sexually transmitted diseases. Moreover, delivery complications were cesarean section, oligohydramnios, chorioamnionitis, and placental abruption. Neonatal complications included prematurity, respiratory distress syndrome, asphyxia, infection, meningitis, sepsis, pneumonia, perinatal mortality, patent arterial duct, necrotizing enterocolitis, IVH, pulmonary hypoplasia, hyperbilirubinemia, and antibiotic intake.
Conclusions: Based on the results of the current study, the most important risk factors for PROM were diabetes and maternal hypertension associated with neonatal and maternal complications. Infection was the most important maternal and neonatal complication.
Full-Text [PDF 522 kb]   (7332 Downloads) |   |   Full-Text (HTML)  (4361 Views)  
Type of Study: Systematic Review |
Received: 2018/02/20 | Accepted: 2018/05/5 | Published: 2019/04/1

1. Caughey AB, Robinson JN, Norwitz ER. Contemporary diagnosis and management of preterm premature rupture of membranes. Reviews in Obstetrics and Gynecology. 2008; 1(1):11-22. [PMID] [PMCID]
2. Okeke TC, Enwereji J, Okoro O, Adiri C, Ezugwu E, Agu P. The incidence and management outcome of Preterm Premature Rupture of Membranes (PPROM) in a tertiary Hospital in Nigeria. American Journal of Clinical Medicine Research. 2014; 2(1):14-7.[DOI:10.12691/ajcmr-2-1-4] [DOI:10.12691/ajcmr-2-1-4]
3. Al Qaqa K, Al Awaysheh F. Neonatal outcome and prenatal antibiotic treatment in premature rupture of membranes. Pakistan Journal of Medical Sciences. 2005; 21(4):441-4.
4. Gahwagi MM, Busarira MO, Atia M. Premature rupture of membranes characteristics, determinants, and outcomes of in Benghazi, Libya. Open Journal of Obstetrics and Gynecology. 2015; 5(09):494-504. [DOI:10.4236/ojog.2015.59072] [DOI:10.4236/ojog.2015.59072]
5. Mercer B, Milluzzi C, Collin M. Periviable birth at 20 to 26 weeks of gestation: Proximate causes, previous obstetric history and recurrence risk. American journal of obstetrics and gynecology. 2005; 193(3):1175-80. [DOI:10.1016/j.ajog.2005.05.040] [DOI:10.1016/j.ajog.2005.05.040]
6. Al Riyami N, Al Ruheili I, Al Shezaw F, Al Khabori M. Extreme preterm premature rupture of membranes: Risk factors and feto maternal outcomes. Oman Medical Journal. 2013; 28(2):108-11. [DOI:10.5001/omj.2013.28] [DOI:10.5001/omj.2013.28]
7. Choudhary M, Rathore SB, Chowdhary J, Garg S. Pre and post conception risk factors in PROM. International Journal of Research in Medical Sciences. 2017; 3(10):2594-8.
8. Goldenberg RL, Hauth JC, Andrews WW. Intrauterine infection and preterm delivery. New England Journal of Medicine. 2000; 342(20):1500-7. [DOI:10.1056/NEJM200005183422007] [DOI:10.1056/NEJM200005183422007]
9. ACOG Committee on Practice Bulletins-Obstetrics. ACOG practice bulletin No. 80: Premature rupture of membranes. Clinical management guidelines for obstetrician-gynecologists. Obstetrics & Gynecology. 2007; 109(4):1007-9. [DOI:10.1097/01.AOG.0000263888.69178.1f] [PMID]
10. Kaye D. Risk factors for preterm premature rupture of membranes at Mulago Hospital, Kampala. East African Medical Journal. 2001; 78(2):65-9. [DOI:10.4314/eamj.v78i2.9090] [DOI:10.4314/eamj.v78i2.9090]
11. Khadijah S, Santoso I, Qana'ah S. Faktor-faktor yang berhubungan dengan kejadian ketuban pecah dini di rsud dr. H. Moch Ansari Saleh Banjarmasin 2015. Dinamika Kesehatan Jurnal Kebidanan Dan Keperawatan. 2016; 7(1):11-20.
12. Dars S, Malik S, Samreen I, Kazi RA. Maternal morbidity and perinatal outcome in preterm premature rupture of membranes before 37 weeks gestation. Pakistan Journal of Medical Sciences. 2014; 30(3):626-9. [PMID] [PMCID]
13. Lee T, Silver H. Etiology and epidemiology of preterm premature rupture of the membranes. Clinics in Perinatology. 2001; 2 8(4):721-34. [DOI:10.1016/S0095-5108(03)00073-3] [DOI:10.1016/S0095-5108(03)00073-3]
14. Shahin M, Raslan H. Comparative study of three amniotic fluid markers in premature rupture of membranes: Prolactin, beta subunit of human chorionic gonadotropin, and alpha-fetoprotein. Gynecologic and Obstetric Investigation. 2007; 63(4):195-9. [DOI:10.1159/000097844] [DOI:10.1159/000097844]
15. Borna S, Borna H, Hantoushzadeh S. Perinatal outcome in preterm premature rupture of membranes with Amniotic fluid index<5 (AFI<5). BMC Pregnancy and Childbirth. 2004; 4(1):15. [DOI:10.1186/1471-2393-4-15] [DOI:10.1186/1471-2393-4-15]
16. Creasy RK, Resnik R, Iams JD. Maternal-fetal medicine: Principles and practice. Houston, Texas: Gulf Professional Publishing; 2004. [PMCID]
17. Diraviyam J. Maternal and perinatal outcome in preterm premature rupture of membranes. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2017; 6(6):2498-502. [DOI:10.18203/2320-1770.ijrcog20172339] [DOI:10.18203/2320-1770.ijrcog20172339]
18. Saremi A, Mosadeq H, Alijani L, Mashhadi khan M. Maternal risk factors of PROM after 37 weeks of pregnancy. Sarem Journal of Medicine. 2012; 1(4):9-14.
19. Maryuni M, Kurniasih D. Risk factors of premature rupture of membrane. Kesmas: National Public Health Journal. 2017; 11(3):133-7. [DOI:10.21109/kesmas.v11i3.1153] [DOI:10.21109/kesmas.v11i3.1153]
20. Doody D, Patterson M, Voigt L, Mueller B. Risk factors for the recurrence of premature rupture of the membranes. Paediatric and Perinatal Epidemiology. 1997; 11(S1):96-106. [DOI:10.1046/j.1365-3016.11.s1.2.x] [DOI:10.1046/j.1365-3016.11.s1.2.x]
21. Mishra S, Joshi M. Premature rupture of membrane- risk factors: A clinical study. Intrnational Journal of Contemporary Medical Research. 2017; 4(1):146-8.
22. Silveira ML, Caminha NdO, Sousa RAd, Pessoa SMF, Gurgel EdPP, Cavalcante DMP. Neonatal outcome in pregnancies that presented premature rupture of membranes. Northeast Network Nursing Journal. 2014; 15(3):491-9. [DOI:10.15253/2175-6783.2014000300014]
23. Boskabadi H, Zakeri Hamidi M, Maamouri G, Najafi A. Frequency of maternal risk factors and neonatal complications of premature rupture of membranes. Journal of Babol University of Medical Sciences. 2016; 18(10):32-9.
24. Sanginabadi M, Seifrabie MA. A comparative evaluation of maternal & neonatal complications in women between outpatients & inpatients with preterm premature rupture of the membranes. Scientific Journal of Hamadan Nursing & Midwifery Faculty. 2014; 22(2):26-32.
25. Boskabadi H, Maamouri G, Mafinejad S. Neonatal complications related with prolonged rupture of membranes. Macedonian Journal of Medical Sciences. 2011; 4(1):93-8.
26. Linehan LA, Walsh J, Morris A, Kenny L, O'Donoghue K, Dempsey E, et al. Neonatal and maternal outcomes following midtrimester preterm premature rupture of the membranes: A retrospective cohort study. BMC Pregnancy and Childbirth. 2016; 16(1):25. [DOI:10.1186/s12884-016-0813-3] [DOI:10.1186/s12884-016-0813-3]
27. Yang LC, Taylor DR, Kaufman HH, Hume R, Calhoun B. Maternal and fetal outcomes of spontaneous preterm premature rupture of membranes. The Journal of the American Osteopathic Association. 2004; 104(12):537-42. [PMID]
28. van der Heyden JL, van der Ham DP, van Kuijk S, Notten KJ, Janssen T, Nijhuis JG, et al. Outcome of pregnancies with preterm prelabor rupture of membranes before 27 weeks' gestation: A retrospective cohort study. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2013; 170(1):125-30. [DOI:10.1016/j.ejogrb.2013.06.012] [DOI:10.1016/j.ejogrb.2013.06.012]
29. Smith GN, Rafuse C, Anand N, Brennan B, Connors G, Crane J, et al. Prevalence, management, and outcomes of preterm prelabour rupture of the membranes of women in Canada. Journal of Obstetrics and Gynaecology Canada. 2005; 27(6):547-53. [DOI:10.1016/S1701-2163(16)30711-3] [DOI:10.1016/S1701-2163(16)30711-3]
30. Heffner LJ, Sherman CB, Speizer FE, Weiss S. Clinical and environmental predictors of preterm labor. Obstetrics and Gynecology. 1993; 81(5(Pt 1)):750-7. [PMID]
31. Chakraborty B, Mandal T, Chakraborty S. Outcome of prelabor rupture of membranes in a tertiary care center in west Bengal. Indian Journal of Clinical Practice. 2013; 24(7):657-62.
32. Nugroho T, Postpartum P. [Obstetrics textbook (Indonesian)]. Yogyakarta: Nuha Medika; 2010.
33. Prawirohardjo S. Ilmu kebidanan. Jakarta: Yayasan bina pustaka sarwono prawirohardjo; 2008.
34. Danforth DN, Gibbs RS. Danforth's obstetrics and gynecology. Philadelphia, Pennsylvania: Lippincott Williams & Wilkins; 2008.
35. Magwali T, Chipato T, Majoko F, Rusakaniko S, Mujaji C. Prophylactic augmentin in prelabor preterm rupture of the membranes. International Journal of Gynecology & Obstetrics. 1999; 65(3):261-5. [DOI:10.1016/S0020-7292(99)00036-3] [DOI:10.1016/S0020-7292(99)00036-3]
36. Romero R, Chaiworapongsa T, Espinoza J. Micronutrients and intrauterine infection, preterm birth and the fetal inflammatory response syndrome. The Journal of Nutrition. 2003; 133(5):1668S-73S. [DOI:10.1093/jn/133.5.1668S] [DOI:10.1093/jn/133.5.1668S]
37. Shrestha SR, Sharma P. Fetal outcome of pre-labor rupture of membranes. Nepal Journal of Obstetrics and Gynaecology. 2006; 1(2):19-24. [DOI:10.3126/njog.v1i2.1489]
38. Movahedi M, Rezaie M, Taefnia AM. Maternal and fetal outcomes of preterm premature rupture of membrane. Journal of Isfahan Medical School. 2013; 30(216):75-6.
39. Gregg AR. Introduction to premature rupture of membranes. Obstetrics and Gynecology Clinics of North America. 1992; 19(2):241-9. [PMID]
40. Medina TM, Hill DA. Preterm premature rupture of membranes: Diagnosis and management. American Family Physician. 2006; 73(4):659-64. [PMID]
41. Parry E. Managing PROM and PPROM. Obstetrics & Gynecology. 2006; 8(4):35-8.
42. Mercer BM, Goldenberg RL, Das AF, Thurnau GR, Bendon RW, Miodovnik M, et al. What we have learned regarding antibiotic therapy for the reduction of infant morbidity after preterm premature rupture of the membranes. Seminars in Perinatology. 2003; 27(3):217-30. [DOI:10.1016/S0146-0005(03)00016-8]
43. Boskabadi H, Saghafi N, Najafi A. Comparing the efficacy of cefotaxime and ampicillin on neonatal infection after premature rupture of membranes. The Iranian Journal of Obstetrics, Gynecology and Infertility. 2014; 17(93):1-9.
44. Uhm S, Alderdice F, Chambers B, Gyte G, Gale C, Duley L, et al. PPO. 23 Top 15 research priorities for preterm birth with clinicians and service users' involvement-outcomes from a James Lind Alliance priority setting partnership. Archives of Disease in Childhood-Fetal and Neonatal Edition. 2014; 99(Suppl 1):A158. [DOI:10.1136/archdischild-2014-306576.463]
45. Weissmann Brenner A, O'Reilly Green C, Ferber A, Divon MY. Values of amniotic fluid index in cases of preterm premature rupture of membranes. Journal of Perinatal Medicine. 2009; 37(3):232-5. [DOI:10.1515/JPM.2009.078] [DOI:10.1515/JPM.2009.078]

Add your comments about this article : Your username or Email:

Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Journal of Pediatrics Review

Designed & Developed by : Yektaweb