Volume 9, Issue 2 (in Press 2021)                   J. Pediatr. Rev 2021, 9(2): 9-9 | Back to browse issues page

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Karami H, Naderisorki M, Ghasemi M, Ghazaiean M. Pancytopenia, as a Presentation of Iron Deficiency: Report of Two Cases and Review of the Literature. J. Pediatr. Rev. 2021; 9 (2) :9-9
URL: http://jpr.mazums.ac.ir/article-1-358-en.html
1- Thalassemia Research Center (TRC), Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran.
2- Thalassemia Research Center (TRC), Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran. , dr.naderisorki@gmail.com
3- Immunogenetics center, Faculty of medicine, Mazandaran University of Medical Sciences, Sari, Iran.
4- Student Research Committe, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Abstract:   (803 Views)
Introduction: One of the most common nutritional deficiencies worldwide is iron deficiency. Fatigue, pallor, vertigo, dyspnea, cold intolerance, lethargy, palpitation, headache and pallor of the mucous membranes or nail beds are the most common symptoms and signs of iron deficiency. Thrombocytosis is commonly seen in iron deficiency anemia, and it seems that erythropoietin plays the main role in this finding. At the other hand, thrombocytopenia and even leukopenia have been reported in iron deficiency, but pancytopenia is a very rare condition.
Case Presentation: In this report, we present two unusual cases of pancytopenia due to severe iron deficiency that improved after treatment with oral iron supplements.
Conclusion: Iron deficiency anemia, if sufficiently severe, may be associated with reduced platelet and leukocyte counts and should be considered as a differential diagnosis in all patients with pancytopenia.
Type of Study: Case Report and Review of Literature | Subject: Pediatrics
Received: 2020/09/18 | Accepted: 2020/10/6 | Published: 2020/10/28

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