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1- Department of audiology, rehabilitation research center, school of rehabilitation sciences, Iran university of medical sciences, Tehran , Iran
2- Department of audiology, rehabilitation research center, school of rehabilitation sciences, Iran university of medical sciences, Tehran , Iran , ahadi.m@iums.ac.ir
Abstract:   (233 Views)
Context:
One of the human desires is to treat children's sensorineural hearing loss with stem cell transplantation. Preclinical studies have been performed in this field and the stem cell types have been tested and achieved relative improvement.
Evidence Acquisition:
This narrative review has been prepared about hearing regeneration with stem cell transplantation. The articles with Full-text and English Language have been searched in PubMed, Scopus, and google scholar from 2000 through 2020 using keywords of sensory neural hearing loss and stem cell.
Results:
In 2018, the first human study was performed with stem cells from the human umbilical cord, which has promising results in terms of the safety of the method and the positive effect on hearing.
Conclusions:
Autologous stem cell transplantation had induced noticeably relative improvement without serious adverse events in children with acquired sensorineural hearing loss. to obtain more evidence, requires further studies with larger sample sizes and population groups.
Full-Text [PDF 1017 kb]   (136 Downloads)    
Type of Study: Narrative Review | Subject: Pediatrics
Received: 2020/09/24 | Accepted: 2021/03/9

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